Taking astragalus along with cyclophosphamide might decrease the effects of cyclophosphamide. Chongqing Medical Journal 2000;29(1):71-72. Shen L, Gwak SR, Cui ZY, Joo JC, Park SJ. Never go off of your diabetes medication until you speak to your doctor. You can choose supplements that meet independent quality standards from ConsumerLab.com, NSF, or USP. In case of overdose, get medical help or contact a Poison Control Center immediately. View abstract. Chen J, Chen SQ. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2004; Wang, H. Report of Clinical Trial of Compount Qishe Tablet: Phase III. Zhou, Y, Huang, Z, Huang, T, and et al. Journal of Medical Theory and Practice 2002;15:510-511. View abstract. Get smarter than stress with a little help from adaptogens. 1995;15(12):707-709. Clin Invest Med 2012;35(1):E1-11. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. If you do experience any negative side effects, consider decreasing your dosage or discontinuing use. So you should avoid using astragalus if you are taking immune-suppressing drugs. With the COVID-19 pandemic, cold and flu season, and lots of other infections and viruses floating around in the air, trying to stay healthy is essential, but it can be so hard when people seem to be getting sick left and right. J Clin Lab Immunol 1988;25:119-23. View abstract. Effect of astragaloside IV on the embryo-fetal development of Sprague-Dawley rats and New Zealand White rabbits. 1991;11(5):265-7, 259. Hebei Medicine 1999;5(5):7-9. View abstract. The University of Maryland Medical Center states that the pediatric dosage is calculated using the standard adult dosage based on a 150-lb. J Pharm Pharmacol 2003;55:1275-82. 2010;62(7):935-942. This can then lead to a dangerous build up of lithium in your body. Though research is limited, it may also help fight viral infections in humans, including the common cold and infection of the liver (11, 12, 13). View abstract. (5) Helping to maintain healthy cholesterol levels (12) 6. Speak to your doctor before you use astragalus supplements to treat your diabetes. Taixiang, W., Munro, A. J., and Guanjian, L. Chinese medical herbs for chemotherapy side effects in colorectal cancer patients. Efficacy and Safety of Astragalus-Containing Traditional Chinese Medicine Combined With Platinum-Based Chemotherapy in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis. View abstract. Journal of Traditional Chinese Medicine 2001;21(3):177-180. View abstract. Creatine therapy in myophosphorylase deficiency (McArdle disease): a placebo-controlled crossover trial. This information may not fit your specific health circumstances. Macrophages are a key part of the body's innate immune response. A randomized, double-blind, multiple-dose escalation study of a Chinese herbal medicine preparation (Dang Gui Buxue Tang) for moderate to severe menopausal symptoms and quality of life in postmenopausal women. Shimizu, N., Tomoda, M., Kanari, M., and Gonda, R. An acidic polysaccharide having activity on the reticuloendothelial system from the root of Astragalus mongholicus. Wang H. Clinical research on Astragalus injection as assisted treatment for refractory heart failure. [Changes in proteinuria, renal function and immunity after treatment with injections of a solution of Astragalus membranaceus]. 4 Given the poor quality . J Anhui University TCM 1998;17(3):18-19. Astragalus root can be taken in a standardized extract, tea or decoction, powdered root, tincture or ointment, all of which have their recommended dosages. Peng, M. H., Wang, X. Y., Sun, F. Y., Du, X. 2009;29(4):313-316. Therapeutic effect observation of Huangqi injection for chronic heart failure. If youre considering taking astragalus, or any supplement, its a good idea to talk to your primary care provider first to identify any potential interactions with prescriptions or over-the-counter medications or supplements. [RETRACTED]. Shi, P. Li Z. Do not give astragalus supplements to a child with a fever as this can make their condition worse. 2012;11:CD003711. Zhao Z, Liu F Yang L. Huangqi injection as the assisted treatment for congestive heart failure. Zhong.Xi.Yi.Jie.He.Za Zhi. It may have some side effects though, such as increased bleeding, so people who have bleeding disorders should be advised before taking this. J Clin Oncol 2006;24:419-30. Endocrine. Zhonghua Er.Ke.Za Zhi. View abstract. View abstract. It can help to prevent heart disease, help your symptoms of fibromyalgia or diabetes, and so much more. These other types of astragalus are generally not used in dietary supplements. I read in Buhners book that astragalus should be avoided In chronic lyme. Hepatoprotective effects of astraglus root. 3. Lishizhen Medicine and Materia Medica Research 2007;18:1743-1744. Astragalus might also be helpful for the kidneys. Zhong Xi Yi Jie He Za Zhi 1991;11(3):150-2, 133. Your lithium dose might need to be changed. Han, Y., Zhang, X. J., and Li, J. Y. View abstract. Qian, Z. W., Mao, S. J., Cai, X. C., Zhang, X. L., Gao, F. X., Lu, M. F., Shao, X. S., Li, Y. Y., Yang, X. K., Zhuo, Y. While further research is needed to confirm the effectiveness of astragalus root, its used for diabetes management in China., Though studies are limited, some evidence points toward astragalus as a means of reducing the symptoms of seasonal allergies. A much lower dose, 0.25 to 0.3 mg, may be more effective for regular use. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Vitamin C. The research on using alternative treatments to treat the common cold is mixed. The following drug interactions can occur with astragalus: Cyclophosphamide (Cytoxan, Neosar): This drug is used to suppress the immune system. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Yuan, Y., Sun, M., and Li, K. S. Astragalus mongholicus polysaccharide inhibits lipopolysaccharide-induced production of TNF-alpha and interleukin-8. View abstract. Hypersenstivity; Effects of Drug Abuse. View abstract. Astragalus, also known as hung q or milkvetch, is most commonly known for its use in traditional Chinese medicine (1, 2). Henan Journal of Chinese Medicine 2001;16:36-37. Hu S. Therapeutic effect observation of Huangqi injection as assisted treatment for chronic heart failure. Zhonghua Jie.He.He.Hu Xi.Za Zhi. Astragalus may support kidney health by improving blood flow and laboratory markers of kidney function, such as measures of protein in the urine. In rare cases, taking Astragalus by mouth can cause rashes, itchy skin, nasal problems or stomach discomfort. View abstract. Dai, F. and Long, Y. C. Combined Chinese and Western treatment of chronic hepatitis B: an analysis of 38 cases [in Chinese]. Proteinuria is a condition in which abnormal amounts of protein are found in urine, which is a sign that the kidneys may be damaged or not functioning normally (28). Gao J. View abstract. View abstract. Effects of Astragalus on cardiac function and hemorrheology in aged patients with congestive heart failure. Therapeutic dose: 2g to 4g a day. Neurotoxic syndromes caused by the ingestion of plants, seeds and fruits]. 2010;21(7):613-620. Chin J Integr.Med 2006;12(4):262-267. Repressed exercise-induced hepcidin levels after danggui buxue tang supplementation in male recreational runners. The earliest recorded references to astragalus are in the Chinese medical literature, dating from 400 to 200 B.C., according to the journal Aging and Disease. 8-7-2009;15(29):3676-3680. 2008;28(6):544-547. Supplements are available as capsules and liquid extracts. World J Gastroenterol 10-7-2005;11(37):5787-5794. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Hypoglycemic effect of astragalus polysaccharide and its effect on PTP1B. Shao BM, Xu W, Dai H, et al. Bao X. Astragalus injection for aged people with congestive heart failure. Z., Luo, Y. J., Sung, C. Y., Chan, C. C., and Lee, T. M. Neural correlates of traditional Chinese medicine induced advantageous risk-taking decision making. ", Chinese Journal of Modern Developments in Traditional Medicine: "Effect of lixu jieyu recipe in treating 75 patients with chronic fatigue syndrome. Based on your chemo recovery plan, your doctor may suggest the use of astragalus supplements in addition to other medications. Sara Nuss is a University of Pittsburgh alumna with a passion for writing and journalism. View abstract. Though theres no official consensus on the most effective form or dosage of astragalus, 930 grams per day is typical (38). Using astragalus will decrease the effectiveness of this drug. The University of Texas has shown it to be an adaptogenic herb which enables viruses, bacteria, and even cancer cells to be "picked up" on the immune system's radar. Lu, Z. M., Qian, X. H., Chen, Z. W., Zhang, C. H., Guo, L. S., and Chen, J. Astragalus root has been used for centuries in traditional Chinese medicine. Doses of up to 60 grams daily have been safely used for up to 4 months. Fish Oil Sleep Side Effects. Though no dosage recommendation exists, up to 60 grams daily for up to four months appears to be safe for most people. World Health Digest 2007;4(11):31-32. People who are pregnant or chestfeeding should not take astragalus, as experts suggest it may be toxic to the parent or child. Zhang D. Therapeutic effect observation of Astragalus injection for the treatment of 42 cases of pulmonary heart failure. Brain Cogn 2009;71(3):354-361. 2003;10(5):1507-1512. Xie, B. X. Dr. Weil says: Go for supplements that contain mostly natural ingredients, not synthetic ingredients. Study on the effects of combined treatment with Radix Astragali injection for infantile viral myocarditis. Chinese Medical Sciences Journal 1995;10(3):146-150. 2005;25(5):400-403. Arch.Pharm.Res. View abstract. Traditional Chinese medicine holds that children with a fever should not take astragalus because it may increase the fever and result in it lasting longer. Sun Y, Hersh EM, Lee SL, et al. Leehey, D. J., Casini, T., and Massey, D. Remission of membranous nephropathy after therapy with Astragalus membranaceus. 3 Several preliminary clinical trials in China have suggested that astragalus can benefit immune function and improve survival in some people with cancer. Guilin Medicine 2001;3:19-20. View abstract. Native to parts of China and a member of the pea family, this bushy perennial plant grows from a hairy stem that produces clusters of small flowers. Kajimura, K., Takagi, Y., Ueba, N., Yamasaki, K., Sakagami, Y., Yokoyama, H., and Yoneda, K. Protective effect of astragali radix by oral administration against Japanese encephalitis virus infection in mice. Its considered an adaptogen. Stegelmeier BL, James LF, Panter KE, et al. Sheng, Z. L., Li, N. Y., and Ge, X. P. [Clinical study of baoyuan dahuang decoction in the treatment of chronic renal failure]. Li S, Hao J Wu F et al. Astragalus root can be taken by children and adults, but the dosage differs according to the type of preparation being used and the size of the individual. Interventions for preventing infection in nephrotic syndrome. Liu, W. J., Liu, B., Guo, Q. L., Zhang, Y. C., Yuan, Y. J., Fu, X. D., Deng, Z. H., and Lin, J. Zhejiang J TCM 1994;29:487-488. It may be, if you're taking up to 60 grams (g) a day by mouth for up to four months. Evid Based Complement Alternat Med. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. J Biol Response Mod 1983;2:227-37.. View abstract. Clinical and experimental effectiveness of Astragali compound in the treatment of chronic viral hepatitis B. J Int Med Res 2009;37(3):662-667. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Cai, X. Y., Xu, Y. L., and Lin, X. J. Zhang H, Huang J. So if you are interested in taking astragalus, you must now be wondering what time of day you should take it so you can get the best results possible. Astragalus increases the activity of the immune system. Immunopharmacology 1990;20(3):225-233. Huh, J. E., Kwon, N. H., Baek, Y. H., Lee, J. D., Choi, D. Y., Jingushi, S., Kim, K. I., and Park, D. S. Formononetin promotes early fracture healing through stimulating angiogenesis by up-regulating VEGFR-2/Flk-1 in a rat fracture model. Qun L, Luo Q, Zhang ZY, et al. Preventive effects of Huangqi on infection in children with nephrotic syndrome. Clinical study of Shengxue Mixture in treating aplastic anemia. Astragalus is considered an adaptogen. Kang GG. 2004;(3):CD003711. Am J Chin Med 1992;20:289-94. and trace minerals. Liu A. View abstract. When taken by mouth: Astragalus is POSSIBLY SAFE for most adults. Acupunct.Electrother.Res 2009;34(1-2):41-73. View abstract. Qu, Z. L., Dong, H., and Wang, S. D. [Effects of astragalus injection on renal function in patients after cardiac valve replacement with cardiopulmonary bypass]. 2004;24(7):589-592. Liu, X., Yang, Y., Zhang, X., Xu, S., He, S., Huang, W., and Roberts, M. S. Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2 cell. Medicine Innovation Research 2008;5(2):102-103. J Ethnopharmacol. Chinese Journal of Information on Traditional Chinese Medicine 1998;5(12):51. Sun Y, Hersh EM, Talpaz M, et al. It has been used in Traditional Chinese Medicine for centuries, being known as Huang Qi. Astragalus root can be taken in a standardized extract, tea or decoction, powdered root, tincture or ointment, all of which have their recommended dosages. Shanxi Medical Journal 2005;34(7):860-861. 1992;12(11):669-71, 645. Analysis the improvement of cardiac function of Astragalus injection for chronic congestive heart failure. View abstract. Liu Z. If you have these conditions, it would be best to speak with a Doctor or TCM Practitioner to see if Astragalus is safe for you to take, and if not, which other herbs might be beneficial instead. Li, S. M., Yan, J. X., and Yang, L. [Effects of Astragalus injection on renal tubular function in patients with IgA nephropathy]. Claudia received her MS in Nutrition from the University of Tennessee Knoxville in 2010. [Clinical and experimental study of yushen jiangtang tablet in treating non-insulin dependent diabetes mellitus]. Journal of Practical Traditional Chinese Medicine 2000;16(4):21. It should only be administered by IV or injection under medical supervision (17). Chin Med J (Engl.) Clin Nephrol 1999;52:333-4. View abstract. Medical Tribune 2006;27:84-85. Yes! Phyllis A. Balch, author of "Prescription for Herbal Healing," states that it works to suppress some immune functions while enhancing others. View abstract. Zhong Xi Yi Jie He Za Zhi 1989;9(11):656-7, 644. View abstract. J Nutr 2006;136(4):899-905. Number of Warfarin sodium and Astragalus reports submitted per year: Common Warfarin Sodium and Astragalus drug interactions by gender *: female: Chronic kidney disease Renal injury Chen, L. X., Liao, J. J Chromatogr.A 4-2-2004;1032(1-2):117-124. Gao, X. H., Xu, X. X., Pan, R., Li, Y., Luo, Y. Zeng J. You can learn more about adrenal dysfunction, as well as how to address and treat it through an at-home protocol, . Speak to your doctor if you have kidney disease and before you use astragalus supplements. View abstract. 2005 - 2023 WebMD LLC. View abstract. Xiangzhe J. Astragalus supplements may be a good option for you if you are looking for a natural, herbal way to treat certain medical issues, with the help of your physician. Information from this source is evidence-based and objective, and without commercial influence. (Chinese Journal of Integrated Traditional and Western Medicine) 1994;14(10):598-600. PLoS.One. 2003;28(1):78-80. Front Pharmacol 2021;12:587021. By subscribing you agree to the Terms of Use and Privacy Policy. J Diabetes Complications 2010;24(3):199-208. 8-15-2007;113(1):132-141. View abstract. 2004;24(1):57-58. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Duan, P. and Wang, Z. M. [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor]. Clinical observation on the effect of Astragalactoside injection in the treatment of infantile viral myocarditis [in Chinese]. would take about 1/4 the adult dose. If you are giving astragalus supplements to a child, always speak to your doctor first to determine the correct dosage. Cheng L, Zhang G, Zhou Y, Lu X, Zhang F, Ye H, Duan J. View abstract. Observation of western medicine combined with Huangqi injection for 36 patients with chronic heart failure. Select a condition to view a list of vitamins. [Effects of Astragalus membranaceus on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action]. Current item Solaray, Astragalus, 550 mg, 100 VegCaps See price in cart. All rights reserved. Journal of Zhenjiang Medical College 2001;11:168-169. [The effect of herbal medicine including astragalus membranaceus (fisch) bge, codonpsis pilosula and glycyrrhiza uralensis fisch on airway responsiveness]. 8-1-1996;12(4):386-393. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. While there are few risks of astragalus use, some side effects have been reported, including: Nausea Diarrhea Itching Rash Runny nose It may be safe for most people to use, but astragalus may. It is an adaptogen, which means it can protect your body from physical, mental, and emotional stress. Is Astragalus safe to take everyday? Xu, Y. F. Efficacy of Astragalus for postponing the deterioration of renal function in patients with diabetic nephropathy. Some medications, such as those used after a transplant, decrease the activity of the immune system. J Nutr Biochem. Z., Chen, J. J., Wu, Z. M., Guo, W. Q., Zhao, L. Y., Qin, L. M., Wang, S. R., and Zhao, Y. R. Clinical and experimental studies of coronary heart disease treated with yi-qi huo-xue injection. Heilongjiang Journal of Traditional Chinese Medicine 2004;3:8-9. Z., Qi, X. L., Zhang, M. X., and Li, Y. P. [Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis]. It has also been shown that astragalus supplements can help to protect your kidneys and be used to treat kidney disease. It may also be injected in a medical setting., While there is still limited research on the health benefits of astragalus, it contains many active plant compounds that may be responsible for its healing properties, like strengthening the immune system and reducing inflammation., The compounds in astragalus may enhance and support your immune system. They also had more significant improvements in symptoms than those receiving standard treatment alone (16). Li, M. Thirty-eight cases of viral myocarditis treated by Sheng Yang Yi Xin decoction [in Chinese]. J Tradit.Chin Med 1989;9(3):193-198. Practical Journal of Medicine and Pharmacology 2006;23:439-440. Harbin Med 1997;17(3):50-52. 2001;21(10):750-751.